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A newly approved drug for Parkinson's disease is a real help for PWCs, said Dr. Jay A. Goldstein. If it continues to be as useful as the initial PWCs have found it, it could very well join his first five or six drugs in his treament protocol.
The new class of drug, called catechol-O-methyltransferase inhibitors (COMP), helps both cognition and energy. You will know after just one 100-mg pill if this treatment is effective for you. Dr. Goldstein is now prescribing 100mg. twice daily for those who find benefits from the medication.
Toleopone, with the common name of Tasmar got USA clearance just this past May. In Europe, a similar drug is available called Comtess. It is not as powerful as Tasmar, however. In the U.S., Comtess is called Comtan. Tasmar is a much more potent inhibitor of COMT and penetrates better into the brain. There do not seem to be any adverse side effects from this medication. The drug has been written up favoribly in the April 25th, 1998 edition of The Lancet (Vol. 351) but of course, refers only to Parkinsonian patients. You may want to request that your physician give you a prescription for just one pill to see if it benefits your energy and cognition.
"Tasmar is more effective (immediately) when combined with a dopamine agonist such as Requip (quinpirol) or a reversible inhibitor of monoamine oxidose (RIMA) such as medlobemide, which due to the wisdom of the FDA, is available in every industrialized counrty in the world but the USA! When it works, it's quite energizing," said Dr. Goldstein.
The following was reported in The National Forum - Summer 1998.
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