2001
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New drug for fatal complication of stem cell transplants

BOSTON -- Sept. 6, 2002 -- A drug extracted from pig intestines reduced the risk of death in patients who experienced a severe and often-fatal complication of stem cell transplants.

Mutations cause resistance to leukemia pill

LOS ANGELES -- August 13, 2002- Researchers have identified specific mutations in a rogue gene that render the drug Gleevec ineffective in some patients who have chronic myeloid leukemia.

Study finds new cause for marrow transplant side effect

ANN ARBOR, Mich. -- June 5, 2002 (Cancer Digest) -- Scientists reported this week that they have discovered how graft-versus-host disease, a common and deadly complication of life-saving bone marrow transplants, attacks patients' own tissue sometimes causing death.

Drug shows promise in common and lethal form of leukemia

BALTIMORE -- June 3, 2002 (Cancer Digest) -- Researchers have shown in mice that a new drug blocks the effect of a cancer-causing gene mutation found in a lethal form of leukemia.

Costly cancer treatment offers no additional benefit to kids

ROCHESTER, NY ­ March 15, 2002 (Cancer Digest)-- A new study refutes a long-held but unproven theory that children suffering from acute lymphoblastic leukemia might suffer less heart damage if treated with longer-lasting infusions of chemotherapy.

Advanced DNA analysis makes more transplants possible

SEATTLE -- Dec. 20, 2001 (Cancer Digest) -- Using the latest DNA analysis techniques, scientists have discovered that some tissue-type mismatches are okay for patients undergoing bone-marrow or stem-cell transplantats to treat leukemia.

Researchers deliver one-two punch to incurable cancer

SEATTLE -- Dec. 10, 2001 (Cancer Digest) -- Using a tag-team approach, researchers believe they may be able to increase survival for patients with multiple myeloma, an incurable form of bone marrow cancer.

Drug therapy leads to long-term remissions in aplastic anemia

BALTIMORE -- Oct. 1, 2001 (Cancer Digest) -- Researchers using a novel drug therapy approach to treating a deadly blood disorder known as aplastic anemia report sustained, treatment-free remissions in an early study of the treatment.

Another disease another promising result for thalidomide

SEATTLE -- Aug. 9, 2001 (Cancer Digest) -- The list of potential benefits for the once banned drug, thalidomide, continues to grow with yet another research team reporting promising results in treating a sometimes fatal blood disorder.

Thalidomide may be effective as first treatment

ROCHESTER, MINN. -- 26-Jul-2001--The early findings of a small clinical trial indicate the drug thalidomide, used as an initial treatment, can stop or slow the progression of a deadly type of blood cancer in newly diagnosed patients.

'Mini-transplants' offers hope for older leukemia patients

SEATTLE -- June 1, 2001 (Cancer Digest) -- People over 50 years of age with leukemia or other potentially fatal blood cancer may now consider a donor stem cell transplant for treatment.

New drug yields promising results for hairy cell leukemia

SEATTLE -- July 25, 2001 (Cancer Digest) -- Another leukemia may be on the verge of yielding to a newly developed drug if early tests are borne out in larger studies.

Painful procedures still used on conscious children

LONDON -- June 21, 2001 (Cancer Digest) -- Many painful bone marrow procedures are carried out in conscious children despite the safety and effectiveness of modern anesthetic and deep sedation techniques, a survey of North America and European cancer centers shows.

Umbilical cord blood transplants effective for adults

CLEVELAND -- June 13, 2001 (Cancer Digest) -- Researchers have for the first time successfully used umbilical cord blood to treat adults suffering from life-threatening forms of leukemia or aplastic anemia.

Homing in on better bone marrow transplants

NEW YORK -- June 11, 2001 (Cancer Digest) -- Researchers have identified a protein that allows cells to "home" to the bone marrow.

'Leukemia pill' wins FDA approval in record time

WASHINGTON ­ May 10, 2001 (Cancer Digest) -- The FDA today announced the approval of "the leukemia pill" a promising new oral treatment for patients with chronic myeloid leukemia (CML) -- a rare life-threatening form of cancer.

FDA approves new treatment for adult leukemia

MONTVILLE, N.J., May 8, 2001 -- The U.S. Food and Drug Administration (FDA) late yesterday cleared an immunotherapy drug for treating patients with the most common form of adult leukemia.

A safe and effective leukemia pill, proves concept

SEATTLE -- Apr. 5, 2001 (Cancer Digest) -- A pill that halts a common type of leukemia has dramatically demonstrated the concept that drugs developed to target the genetic defects that underlie many types of disease can be effective.

Experimental drug shows promise for curing rare leukemia

NEW ORLEANS, Mar. 27, 2001 (Cancer Digest) -- Early tests in humans of a new compound show promising results for patients with a rare form of blood cancer say researchers at the National Cancer Institute.

Leukemia patients live longer with blood cell transplants than with marrow transplantation

SEATTLE--Jan. 18, 2001 -- Patients treated with leukemia survive longer when treated with cells tranplanted from circulating blood than patients treated with marrow transplants, say researchers in Seattle.

Killing Leukemia Cells By Their Own Sword

SAN DIEGO -- Feb. 1, 2000 -- (Cancer Digest) Edging ever closer to a cure for a common form of leukemia, researchers have discovered a way to use the gene that causes blood cells to become cancerous in the first place, to trick them into committing suicide.

Discovery could boost marrow transplantion success

SEATTLE, 05-Feb-1999 -- (Cancer Digest) Researchers in Israel have for the first time revealed a homing mechanism that guides transplanted marrow cells from the blood to bone marrow where they reconstitute the blood and immune systems.

Antibody-linked chemotherapy targets leukemia

MIAMI, FL., Dec. 7, 1998 -- (Cancer Digest) A new breakthrough drug specifically targets leukemic cells and works as well as standard therapies but with milder side effects.

Genetic tissue matching improves marrow tranplant outcomes

(Cancer Digest -- 8-Nov. 1998) In the largest United States study ever conducted of unrelated marrow transplants for leukemia, researchers found that using genetic techniques for matching patients with marrow donors could dramatically improve survival.


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